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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCK All Species: 34.24
Human Site: Y489 Identified Species: 83.7
UniProt: P06239 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P06239 NP_001036236.1 509 58001 Y489 E D R P T F D Y L R S V L E D
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087049 602 68092 Y582 E E R P T F D Y L Q S V L D D
Dog Lupus familis XP_851972 509 58073 Y489 E D R P T F D Y L R S V L E D
Cat Felis silvestris
Mouse Mus musculus P06240 509 57924 Y489 E D R P T F D Y L R S V L D D
Rat Rattus norvegicus Q01621 509 57871 Y489 E D R P T F D Y L R S V L D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514812 514 58948 Y494 E E R P T F D Y L Q S V L D D
Chicken Gallus gallus P42683 508 58121 Y488 E E R P T F E Y M K S V L E D
Frog Xenopus laevis P13406 537 60828 Y515 E E R P T F E Y L Q G F L E D
Zebra Danio Brachydanio rerio NP_001035418 503 57487 F482 D N R P T F E F L R S V L E D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9J3 517 59051 T495 M R R P T F E T L Q W K L E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 55.8 97.4 N.A. 96.8 96.6 N.A. 63 82.1 54.5 69.7 N.A. 50 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 68.5 98.6 N.A. 98.2 98 N.A. 78.7 91.9 69.8 82.7 N.A. 67.1 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 80 100 N.A. 93.3 93.3 N.A. 80 73.3 66.6 73.3 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 100 86.6 100 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 40 0 0 0 0 60 0 0 0 0 0 0 40 100 % D
% Glu: 80 40 0 0 0 0 40 0 0 0 0 0 0 60 0 % E
% Phe: 0 0 0 0 0 100 0 10 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 90 0 0 0 100 0 0 % L
% Met: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 40 0 0 0 0 0 % Q
% Arg: 0 10 100 0 0 0 0 0 0 50 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 80 0 0 0 0 % S
% Thr: 0 0 0 0 100 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 80 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _